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. 2014 Mar 13;63(4):1340–1352. doi: 10.2337/db13-1139

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© 2014 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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Otop1 physically interacts with STAT1 and regulates IFN-γ response in adipocytes. Immunoblots of total cell lysates and immunoprecipitated (IP) proteins (anti-HA) from differentiated 3T3-L1 adipocytes (A) or brown adipocytes (B) stably expressing vector or Flag-HA-tagged Otop1 and treated with vehicle or IFN-γ. (C) Immunoblots of total cell lysates from brown adipocytes stably expressing vector or Otop1 treated with saline (-) or IFN-γ (+) for indicated time. Vec, vector; FHO, Flag-HA-tagged Otop1.