Table 1.
Blood
|
Kidney
|
Urine
|
Liver
|
Bowelb
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
18F | 131I-OIH | 18F | 131I-OIH | 18F | 131I-OIH | % 18F / 131I-OIH | 18F | 131I-OIH | 18F | 131I-OIH | |
Group A | |||||||||||
10 min | 8.5 ± 0.8c | 5.1 ± 0.5 | 4.6 ± 0.8d | 5.3 ± 1.2 | 29.3 ± 3.7c | 50.8 ± 5.2 | 58 ± 4 | 2.3 ± 0.4c | 3.3 ± 0.2 | 1.2 ± 0.3d | 1.7 ± 0.5 |
60 min | 1.6 ± 0.3c | 0.8 ± 0.1 | 1.9 ± 0.4c | 0.7 ± 0.4 | 78.6 ± 4.8c | 85.4 ± 3.1 | 92 ± 3 | 0.7 ± 0.1e | 0.6 ± 0.2 | 0.7 ± 0.1c | 1.8 ± 0.3 |
Group B | |||||||||||
60 min | 13.5 ± 0.7c | 15.1 ± 0.9 | 0.4 ± 0.1e | 0.5 ± 0.2 | - | - | - | 4.0 ± 0.2c | 7.1 ± 0.6 | 3.2 ± 0.6c | 7.6 ± 1.1 |
Data are presented as mean ± SD.
(10 min n=7, 60 min n=5, lig.ped. 60 min n=5).
Bowel includes intestines and stomach.
P < 0.001,
P < 0.05 and
P > 0.07, comparison of biodistribution between Al18F-NODA-butyric acid and 131I-OIH.