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. Author manuscript; available in PMC: 2014 May 13.
Published in final edited form as: Sci Transl Med. 2013 Nov 13;5(211):211ra158. doi: 10.1126/scitranslmed.3006627

Fig. 1. Longitudinal whole-body dual-energy x-ray absorptiometry (DEXA)–derived measures of areal BMD (aBMD) (A and C) and BMC (B and D), collected in female (A and B) and male (C and D) mice.

Fig. 1

Scans were collected biweekly beginning at 4.5 weeks of age until 16.5 weeks of age in wild-type mice (circles; solid line), Sost−/− mice (triangles; dotted line), Lrp5−/− mice (inverted triangles; dashed line), and Sost−/− Lrp5−/− double knockouts (squares; interrupted dashed line). *P < 0.05, significant difference from wild-type mice; †P < 0.05, significant difference from Lrp5−/− mice; ‡P < 0.05, significant difference from Sost−/− mice, using repeated-measures analysis of variance (ANOVA). For each group, n = 9 to 14 mice.