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Phosphorylated ERK1/2 protein levels (measured at 44/42 kDa) in the NAc (A), CPu (B), PfC (C), and HIP (D) of male and female rats after CPP testing. Phosphorylated protein levels are expressed as a ratio to their respective total protein levels (normalized to a tubulin, 55 kDa)(±SEM) (n = 4 animals per group). *Indicates significant difference from saline controls of the same sex at p < 0.05. #Indicates significant difference between male and female saline animals at p < 0.05.
