Table 3.
pERK | pCREB | FosB | ΔFosB | |||||
---|---|---|---|---|---|---|---|---|
Male | Female | Male | Female | Male | Female | Male | Female | |
NAc | 112.8±1.6 | 122.9±3.8 | 118.1±3.7 | 118.4±5.3 | 112.8±7.4 | 110.9±13.7 | 138.2±11.1 | 17.8±4.2 |
CPu | 103.9±2.8 | 124.3±3.1 | 104.6±8.8 | 94.2±4.7 | 142.0±10.3 | 173.3±6.1# | 124.9±5.4 | 173.8±6.2# |
PfC | 111.7±5.4 | 138.1±3.0 | 122.6±6.6 | 104.3±3.1 | 108.1±4.2 | 106.0±3.8 | 105.6±1.3 | 103.2±1.9 |
HIP | 122.0±3.2 | 166.9±8.3# | 100.8±8.5 | 108.1±8.6 | 98.4±9.5 | 118.6±17.1 | 101.2±2.1 | 101.7±2.3 |
Data are presented as densitometric units expressed as a mean percentage of saline controls of the respective sex which were set to 100% (± SEM) (n = 4 animals per group). Bold values indicate a significant difference between cocaine treated males and females (p < .05). Bold
indicates cases in which a significant (p < .05) difference between saline and cocaine animals was observed prior to expressing data as a percent of saline.