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. 2014 Mar 11;2014:701013. doi: 10.1155/2014/701013

Figure 3.

Figure 3

Probe-based confocal laser endomicroscopy (pCLE) patterns observed in GI-GVHD patients following intravenous injection of fluorescein. (a) Normal sigmoid, (b) abnormal microvessel network with dilation of a microvessel surrounding a colonic crypt (mild GVHD), (c) mild increase in fluorescein intensity in the lamina propria (mild GVHD), (d) distorted crypts (moderate GVHD), and ((e), (f)) major architectural changes showing proliferation and dilation of microvessels in the lamina propria, major fluorescein extravasation, and complete destruction of the colonic crypt architecture (severe GVHD).