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. 2014 Apr;20(4):447–461. doi: 10.1261/rna.043034.113

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© 2014 Padlan et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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FIGURE 7. — Cation binding sites in Lys1.2minE. (A) Coordination geometry of Na⁺ to surrounding atoms that stabilize loops 1 and 2. (B) The effect of monovalent cation type on lysozyme affinity. (C) Locations of the two ordered Mg²⁺ ions in the regions of the most negative electrostatic potential in the loops of the RNA. Water molecules are depicted as purple spheres.