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. 2013 Nov 16;42(Database issue):D450–D458. doi: 10.1093/nar/gkt1151

Figure 2.

Figure 2.

Screenshot depicting an example run of the CR Cistrome database. Assuming the user is interested in PHF8 in human fibroblasts, step 1 will return a page containing the basic information on PHF8, including its alias, introduction, functions and disease associations, which are manually generated from the literature and also external links to NCBI, UniProt, Wikipedia and GeneCards are provided, as well as ChIP-Seq data information and ChIP-Seq data information for the related HMs in human fibroblasts. Step 2 will provide a page containing the top three motifs for PHF8 in human fibroblasts and the average profile near the TSS and TTS as well as the average gene profile, genome enrichment, average conservation profile across PHF8 ChIP-Seq peaks and a brief data summary, which could help indicate the general quality of this data set. Step 3 will generate PHF8 data set id and H3K4me3 data set id for each comparison as well as the Venn diagram, distribution of their overlap peaks, the average PHF8 and H3K4me3 ChIP-Seq signal profile in PHF8’s binding sites and the reads density plot of PHF8 and H3K4me3 in PHF8’s binding sites.