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. 2013 Oct 30;42(Database issue):D320–D325. doi: 10.1093/nar/gkt1010

Figure 1.

Figure 1.

The largest PPI network in IDEAL. The rectangles indicate proteins (IDEAL entries), and are colored green if they contain at least one ProS. Otherwise, they are colored blue. Users can know the protein name and the PDB entry of the complex by moving the pointer on the node and edge (the red box and the red line), respectively. The networks surrounded by ellipse a involve cell cycle–related proteins (32), those enclosed by ellipse b involve nuclear receptors and their corepressors/activators (33), those surrounded by c involve histone-related proteins (34) and those enclosed by d involve proteins binding with importin (35). Abbreviations for proteins are as follows: p53, cellular tumor antigen p53 (IID00015); CBP, CREB-binding protein (IID50008); p300, histone acetyltransferase p300 (IID00070); CDK2, cyclin-dependent kinase 2 (IID00034); p27, cyclin-dependent kinase inhibitor 1B (IID00049); Rb, retinoblastoma-associated protein (IID00017); ANDR, androgen receptor (IID00020); GLCR, glucocorticoid receptor (IID00014); NRCR1, nuclear receptor corepressor 1 (IID00189); NRCA4, nuclear receptor coactivator 4 (IID00074); H2, histone H2B type 1-K (IID00010); H3.3, histone H3.3 (IID00239); H4, histone H4 (IID00058); SETD8, N-lysine methyltransferase SETD8 (IID00101); BPTF, nucleosome-remodeling factor subunit BPTF (IID00071); and importin α, importin subunit alpha-2 (IID50009).