Table 1.

Data collection and refinement statistics

	WDR5-MM-401
Data collection
Space group	P1
Cell dimensions
a, b, c (Å)	46.904, 47.242, 68.896
α, β, γ (°)	88.50, 89.50, 74.53
Resolution (Å)	2.1
Rsym (Å) (high res. Shell)	0.060(0.167)
I/σI (high res. Shell)	14.2 (3.9)
Completeness (%)(high res. Shell)	97.8 (94.9)
Redundancy (high res. Shell)	1.9 (1.7)
Refinement
Resolution (Å)	37.8–2.1
No. reflections	32442
R work/R free (%)	15.9/20.8
No. atoms
WDR5	4799
MM-401	84
Water	523
B-factor (Å2)
WDR5	17.719
MM-401	14.53
Water	25.401
R.m.s. deviations
Bond lengths (Å)	0.004
Bond angles (°)	0.919