Table 3.
Zebrafish Class I putative peptide anchor residues
N-terminus | C-terminus | ||||||||
---|---|---|---|---|---|---|---|---|---|
| |||||||||
7 | 59 | 159 | 171 | 84 | 123 | 143 | 146 | 147 | |
HLA | Y | Y | Y | Y | Y | Y | T | K | W |
Fish | Y | Y | Y | Y | R | F | T | K | W |
Uaa | Y | Y | Y | Y | R | F | T | K | W |
Uba | A | Y | Y | Y | R | F | T | K | W |
Uca | A | Y | Y | Y | R | F | T | K | W |
Uda | Y | Y | Y | Y | R | F | T | K | W |
Uea | Y | Y | Y | Y | R | F | T | N | W |
Ufa | V | F | Y | Y | R | F | T | K | W |
Uga | Y | Y | Y | Y | R | F | T | K | W |
Uha | A | Y | Y | Y | R | F | T | K | L |
Uia | Y | Y | Y | Y | R | W | T | N | W |
Uja | Y | F | Y | Y | R | F | T | K | W |
Uka | A | Y | Y | Y | R | F | T | K | W |
Putative peptide anchor residues, based on an alignment with other vertebrate Class I MHC genes. HLA represents a consensus of classical human Class I sequences (HLA-A, B, C). Fish represents a consensus sequence from teleost Class I MHC genes thought to be classical. Anchor residue numbering is based on the human HLA-A2 gene