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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Mol Cancer Ther. 2013 May 23;12(8):1471–1480. doi: 10.1158/1535-7163.MCT-12-1227

Figure 2.

Figure 2

MNP-CUR formulation efficiently inhibits tumor growth and increases survival of HPAF-II tumor xenograft bearing mice. (A) Single time intratumoral dose of MNP-CUR (20 μg in PBS) more efficiently inhibited growth of HPAF-II tumor xenografts as compared to free curcumin (20 μg in Tween 20) and controls (blank MNPs and Tween 20). Representative photographs of tumor bearing mice are shown as inset. (B) Photomicrographs of MNP-CUR treated tumors that were processed for Prussian blue staining. (C) Kaplan–Meier survival plot of mice treated with Tween 20, MNPs, curcumin (CUR) and MNP-CUR. Data represents at least 6 mice/group (Mean ± SEM), *P < 0.05.