Table 1. Ten chemicals with the strongest links to diabetes (including all three layers of information). D Score is from the disease similarity layer, GWAS score is based on SNPs information, the Combined score includes both computational layers, and the NTP evidence relies on literature documentation from a recent published review.

	D score	GWAS score	Combined score	NTP evidence*
TCDD	0.250	0.574	0.412	1
HCB	0.500	0.019	0.259	1
Bisphenol A	0.250	0.167	0.208	1
DDT	0.375	0.019	0.197	1
PFOA	0.250	0.130	0.190	1
PFOS	0.250	0.130	0.190	1
MBP	0.250	0.019	0.134	1
Arsenic	0.125	0.111	0.118	1
Dioxins	0.125	0.019	0.072	1
MEHP	0.125	0.019	0.072	1

*1 if the association T2D-chemical has been reported in the literature.