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. 2014 Mar 25;9(3):e92794. doi: 10.1371/journal.pone.0092794

Table 1. Demographic and clinical characteristics of the participating men according to IIEF-5 score.

Non-ED (N = 197) Mild ED (N = 642) Mo-Se ED(N = 123) Asexuality(N = 569) P
Normal data a Mean ±SD
 Age 56.84±8.92 59.77±8.63* 63.06±8.54* 65.70±8.20* <0.001
 BMI 24.17±3.54 24.34±3.48 24.50±3.12 24.17±3.66 0.705
 WC 83.03±6.95 82.82±8.81 84.41±6.49 82.44±7.22 0.091
 Systolic BP 128.36±16.04 129.58±15.04 128.63±15.50 132.16±17.72* 0.005
 Diastolic BP 82.25±8.97 82.39±8.87 81.69±9.52 81.76±9.47 0.625
 HR 74.14±4.58 73.76±5.65 74.09±5.50 74.08±5.59 0.703
 IIEF-5 23.22±0.96 17.07±2.62* 8.13±2.22* <0.001
 FBG 5.51±1.71 5.53±1.58 5.59±1.52* 5.95±2.34 0.070
 Creatinine 74.73±10.49 75.32±13.02 75.19±10.35 76.97±17.01 0.114
 TT 4.52±2.97 4.49±2.37 4.45±2.15 4.19±2.19 0.629
Non-normal data b Median (min-max)
 TPSA 0.67 (0.09–13.20) 0.74 (0.09–15.60) 0.82 (0.09–24.00)* 1.04 (0.09–48.00)* <0.001
 FSH 5.43 (1.04–60.70) 6.52 (0.43–69.01) 4.65 (0.52–44.70)* 6.80 (0.46–60.70) <0.001
 LH 4.19 (0.30–40.70) 3.79 (0.20–30.20) 3.63 (0.79–20.90) 3.13 (0.36–21.90) 0.022
 PRL 6.88 (0.48–51.27) 7.62 (0.48–252.30) 7.35 (0.83–34.84) 7.78 (0.54–120.20) 0.555
 E2 12.00 (12.00–139.00) 12.00 (0.69–122.00) 12.00 (12.00–104.00) 12.00 (12.00–215.00) 0.813
 T/E2 0.25 (0.03–1.17) 0.26 (0.01–4.74) 0.26 (0.02–0.77) 0.22 (0.01–2.68) 0.359
 ALT 18.00 (5.00–178.00) 18.00 (3.00–132.00) 18.00 (4.00–86.00) 19.00 (4.00–196.00) 0.913
 TG 1.50 (0.48–19.23) 1.45 (0.45–15.00) 1.52 (0.43–6.48) 1.52 (0.41–12.54) 0.400
Lifestyle c N (%)
 Exercises 75 (38.1) 275 (42.8) 58 (47.2) 241 (42.4) 0.440
 Alcohol 72 (36.5) 233 (36.3) 50 (40.7) 191 (33.6) 0.457
 Tea 116 (58.9) 403 (62.8) 80 (65.0) 308 (54.1) 0.011
 Smoking 108 (54.8) 326 (50.8) 55 (44.7) 273 (48.0) 0.235
Chronic disease c
 Diabetes 15 (7.6) 70 (10.9) 20 (16.3) 94 (16.5)* 0.002
 Hypertension 52 (26.4) 212 (33.0) 47 (38.2) 222 (39.0)* 0.007
 Dyslipidemia 16 (8.1) 54 (8.4) 15 (12.2) 46 (8.1) 0.511
 BPH 9 (4.6) 42 (6.5) 18 (14.6)* 44 (7.7) 0.006
 PLS 2 (1.0) 24 (3.7) 7 (5.7) 23 (4.0) 0.133

Abbreviations: ED, erectile dysfunction; Mo-Se: moderate to severe; BMI, body mass index; WC, waist circumference; BP, blood pressure; HR, heart rate; IIEF-5, 5-item form of International Index of Erectile Function; FBG, fast blood glucose; TT, total testosterone;TPSA, total prostate specific antigen; FSH, follicle-stimulating hormone; LH, luteotropic hormone; PRL, prolactin; E2, Estradiol; ALT, alanine transferase; TG, triglyceride; BPH, benign prostatic hyperplasia; PLS, prostatatis-like symptom; SD, standard deviation, Min, minimal; Max, maximum.

a

Data met normal distribution, using One-Way ANOVA analysis;

b

Data met non-normal distribution, using K-independent samples analysis;

c

Ranked data, using Chi-square tests analysis.

Bonferroni correction p: original p×4; *vs. Non-ED, p<0.05; vs. Mo-Se ED, p<0.05.