Table 1. Demographic and clinical characteristics of the participating men according to IIEF-5 score.
Non-ED (N = 197) | Mild ED (N = 642) | Mo-Se ED(N = 123) | Asexuality(N = 569) | P | |
Normal data a | Mean ±SD | ||||
Age | 56.84±8.92 | 59.77±8.63*† | 63.06±8.54* | 65.70±8.20*† | <0.001 |
BMI | 24.17±3.54 | 24.34±3.48 | 24.50±3.12 | 24.17±3.66 | 0.705 |
WC | 83.03±6.95 | 82.82±8.81 | 84.41±6.49 | 82.44±7.22† | 0.091 |
Systolic BP | 128.36±16.04 | 129.58±15.04 | 128.63±15.50 | 132.16±17.72* | 0.005 |
Diastolic BP | 82.25±8.97 | 82.39±8.87 | 81.69±9.52 | 81.76±9.47 | 0.625 |
HR | 74.14±4.58 | 73.76±5.65 | 74.09±5.50 | 74.08±5.59 | 0.703 |
IIEF-5 | 23.22±0.96 | 17.07±2.62* | 8.13±2.22* | – | <0.001 |
FBG | 5.51±1.71 | 5.53±1.58 | 5.59±1.52* | 5.95±2.34 | 0.070 |
Creatinine | 74.73±10.49 | 75.32±13.02 | 75.19±10.35 | 76.97±17.01 | 0.114 |
TT | 4.52±2.97 | 4.49±2.37 | 4.45±2.15 | 4.19±2.19 | 0.629 |
Non-normal data b | Median (min-max) | ||||
TPSA | 0.67 (0.09–13.20) | 0.74 (0.09–15.60) | 0.82 (0.09–24.00)* | 1.04 (0.09–48.00)*† | <0.001 |
FSH | 5.43 (1.04–60.70) | 6.52 (0.43–69.01) | 4.65 (0.52–44.70)* | 6.80 (0.46–60.70)† | <0.001 |
LH | 4.19 (0.30–40.70) | 3.79 (0.20–30.20) | 3.63 (0.79–20.90) | 3.13 (0.36–21.90)† | 0.022 |
PRL | 6.88 (0.48–51.27) | 7.62 (0.48–252.30) | 7.35 (0.83–34.84) | 7.78 (0.54–120.20) | 0.555 |
E2 | 12.00 (12.00–139.00) | 12.00 (0.69–122.00) | 12.00 (12.00–104.00) | 12.00 (12.00–215.00) | 0.813 |
T/E2 | 0.25 (0.03–1.17) | 0.26 (0.01–4.74) | 0.26 (0.02–0.77) | 0.22 (0.01–2.68) | 0.359 |
ALT | 18.00 (5.00–178.00) | 18.00 (3.00–132.00) | 18.00 (4.00–86.00) | 19.00 (4.00–196.00) | 0.913 |
TG | 1.50 (0.48–19.23) | 1.45 (0.45–15.00) | 1.52 (0.43–6.48) | 1.52 (0.41–12.54) | 0.400 |
Lifestyle c | N (%) | ||||
Exercises | 75 (38.1) | 275 (42.8) | 58 (47.2) | 241 (42.4) | 0.440 |
Alcohol | 72 (36.5) | 233 (36.3) | 50 (40.7) | 191 (33.6) | 0.457 |
Tea | 116 (58.9) | 403 (62.8) | 80 (65.0) | 308 (54.1) | 0.011 |
Smoking | 108 (54.8) | 326 (50.8) | 55 (44.7) | 273 (48.0) | 0.235 |
Chronic disease c | |||||
Diabetes | 15 (7.6) | 70 (10.9) | 20 (16.3) | 94 (16.5)* | 0.002 |
Hypertension | 52 (26.4) | 212 (33.0) | 47 (38.2) | 222 (39.0)* | 0.007 |
Dyslipidemia | 16 (8.1) | 54 (8.4) | 15 (12.2) | 46 (8.1) | 0.511 |
BPH | 9 (4.6) | 42 (6.5) | 18 (14.6)* | 44 (7.7) | 0.006 |
PLS | 2 (1.0) | 24 (3.7) | 7 (5.7) | 23 (4.0) | 0.133 |
Abbreviations: ED, erectile dysfunction; Mo-Se: moderate to severe; BMI, body mass index; WC, waist circumference; BP, blood pressure; HR, heart rate; IIEF-5, 5-item form of International Index of Erectile Function; FBG, fast blood glucose; TT, total testosterone;TPSA, total prostate specific antigen; FSH, follicle-stimulating hormone; LH, luteotropic hormone; PRL, prolactin; E2, Estradiol; ALT, alanine transferase; TG, triglyceride; BPH, benign prostatic hyperplasia; PLS, prostatatis-like symptom; SD, standard deviation, Min, minimal; Max, maximum.
Data met normal distribution, using One-Way ANOVA analysis;
Data met non-normal distribution, using K-independent samples analysis;
Ranked data, using Chi-square tests analysis.
Bonferroni correction p: original p×4; *vs. Non-ED, p<0.05; †vs. Mo-Se ED, p<0.05.