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. 2014 Mar 25;9(3):e92813. doi: 10.1371/journal.pone.0092813

Table 1. Summary of proteins differentially expressed in mouse muscle tissue infected by Chikungunya virus.

Spot intensity Mean± SD
S.No Spot ID Protein Identified Accessiona Mowse Scoreb PMF/MS-MS % Covc Peptides Matched (searched) Mr/pI theoretical Mr/pI observed Mock Infected CHIKV Infected Fold change Mean± SD P value
1 M1 Vimentin P20152 290/530 77 59 (132) 53.68/5.06 63/4.9 5.8±1.7 18.5±6.4 3.15±0.41 8×10−3
2 M2 a.Albumin b.Kininogen P07724 O08677 132/NA 86/77 59 51 36 (119) 31 (119) 53.17/4.88 95/5.2 3.6±1.2 8.2±1.7 2.6±0.82 1×10−2
3 M3 Vimentin P20152 241/241 85 61 (176) 53.5/5.06 70/5.2 5.4±2.3 26±11.4 4.5±2.3 3×10−2
4 M4 Kininogen O08677 105/NS 56 28 (147) 47.8/5.74 95/5.2 6.1±1.3 14.9±1.7 2.6±0.9 9×10−3
5 M5 Vimentin P20152 214/73 73 54 (173) 51.5/4.9 75/5.0 6.9±1.6 17.6±5.8 2.6±0.7 1×10−2
6 M6 Haptoglobin Q3UBS3 64/117 54 21 (129) 38.8/6.08 52/5.0 0 5.4±1.4 DIV/0e 6×10−3
7 M7 Myosin Q5SX40 120/58 48 95 (167) 60.9/5.4 92/5.4 4.9±1.9 12.2±3.0 2.3±0.8 1×10−2
8 M8 Vimentin P20152 262/219 89 65 (162) 51.5/4.96 72/5.3 27.7±4.3 52±9.2 2±0.6 5×10−3
9 M9 Vimentin Q5FWJ3 265/474 89 77 (181) 53.6/5.06 72/5.3 16.2±2.5 35.9±8.1 2.3±0.9 5×10−3
10 M10 Vimentin P20152 217/337 83 64 (178) 53.6/5.06 72/5.4 30±1.6 101±37.4 3.4±1.2 9×10−3
11 M11 Actin P60710 160/215 82 37 (125) 41.7/5.3 57/5.6 17.5±4.3 36.4±3.9 2.3±0.9 1×10−3
12 M12 a.Albumin b.Hemopexin P07724 Q91X72 154/NA 98/417 71 56 54 (164) 27 (164) 50.51/7.32 95/6.3 41.5±12 81±27.05 1.9±0.04 4×10−2
13 M13 a.Hemopexin b.Albumin Q91X72 P07724 152/404 114/NA 63 69 31 (126) 46 (126) 51.3/7.92 95/6.4 17.5±6.8 53±14.6 3.4±1.8 4×10−3
14 M14 Hemopexin Q91X72 170/55 51 25 (108) 51.3/7.92 95/6.5 13±7.9 40±12.2 3.6±1.2 9×10−3
15 M15 Hemopexin Q91X72 211/115 58 29 (111) 51.3/7.92 95/6.7 5.67±0.7 35.5±6.3 6.4±1.9 2×10−2
16 M16 Glucose regulated protein P27773 203/421 69 45 (170) 56.59/5.78 72/6.4 21.4±3.6 40.1±6.8 1.9±0.4 2×10−3
17 M17 Pyruvate kinase isozyme M2 P52480 120/84 83 35 (159) 43.1/5.88 58/6.4 3.9±0.43 11.5±3.2 3.0±1.1 3×10−3
18 M18 Fibrinogen Q3TGR2 110/124 66 42 (182) 54.7/6.68 78/6.7 12±1.7 22±1.0 1.85±0.18 3×10−2
19 M19 Apolipoprotein A-1 Q3V2G1 120/268 60 24 (147) 30.66/5.64 34/5.9 18.7±7.1 66.3±4.0 3.9±1.2 2×10−5
20 M20 Peroxiredoxin-6 O08709 176/306 88 30 (119) 24.7/5.72 36/6.5 7.2±0.9 23.6±5.9 3.8±0.5 1×10−4
21 M21 Heat shock protein 25 P14602 117/160 71 18 (110) 23/6.12 36/6.7 11.4±3.8 40.6±10 3.8±1.6 9×10−3
22 M22 Rho GDP dissociation inhibitor 2 Q61599 92/37 81 17 (97) 22.7/4.97 34/5.1 3.4±0.7 10±0.96 3.0±0.6 3×10−5
23 M23 Actin P60710 NS/55 NA NA 39/5.8 26/5.3 0 7.6±1.2 DIV/0e 1×10−5
24 M24 Actin related protein Q6ZQK2 64/90 37 65 (180) 191.2/6.15 26/6.3 0 4.7±0.95 DIV/0e 5×10−4
25 M25 NAd NA NA NA NA NA NA 23.8±5.3 94.5±11 4.1±0.7 2×10−5
26 M26 Tropomyosin alpha chain P58772 167/420 70 35 (129) 32.8/4.6 50/4.8 512.6±22 208±15 0.4±0.3 5×10−3
27 M27 Tropomyosin alpha chain P58772 126/323 69 31 (142) 32.6/4.8 45/4.9 637±128 284.5±52 0.5±0.1 2×10−3

a = Swiss Prot accession number. b =  By MASCOT. c =  % Coverage of the identified sequence. NAd  =  not available. DIV/0e =  Divided by zero. Sopt ID represents the number on 2-DE gels. NS = Non significant.