Table 2. Distributions of alleles and genotypes of the MIF polymorphisms among patients with Graves disease and healthy controls.

		Graves disease, goiter grade
Polymorphisms, n (%)	Healthy	0	1a	1b	2	3	P value
rs5844572 -794(CATT)n
5	142	23	15	39	200	41	0.988 a
	(36.2)	(35.9)	(28.8)	(36.1)	(32.7)	(32.5)	0.990 b
6	192	32	27	54	315	63
	(49.0)	(50.0)	(51.9)	(50.0)	(51.5)	(50.0)
7	54	9	10	15	92	21
	(13.8)	(14.1)	(19.2)	(13.9)	(15.0)	(16.7)
8	4	0	0	0	5	1
	(1.0)	(0.0)	(0.0)	(0.0)	(0.8)	(0.8)
5/5	19	2	2	9	29	5	0.968 a
	(9.7)	(6.3)	(7.7)	(16.7)	(9.5)	(7.9)	0.992 b
5/6	74	14	8	16	116	21
	(37.8)	(43.8)	(30.8)	(29.6)	(37.9)	(33.3)
5/7	26	5	3	5	25	9
	(13.3)	(15.6)	(11.5)	(9.3)	(8.2)	(14.3)
5/8	4	0	0	0	1	1
	(2.0)	(0.0)	(0.0)	(0.0)	(0.3)	(1.6)
6/6	48	7	7	15	74	17
	(24.5)	(21.9)	(26.9)	(27.8)	(24.2)	(27.0)
6/7	22	4	5	8	48	8
	(11.2)	(12.5)	(19.2)	(14.8)	(15.7)	(12.7)
6/8	0	0	0	0	3	0
	(0.0)	(0.0)	(0.0)	(0.0)	(1.0)	(0.0)
7/7	3	0	1	1	9	2
	(1.5)	(0.0)	(3.8)	(1.9)	(2.9)	(3.2)
7/8	0	0	0	0	1	0
	(0.0)	(0.0)	(0.0)	(0.0)	(0.3)	(0.0)
rs755622 G-173C
G	76	17	10	13	90	20	0.068 a
	(19.4)	(26.6)	(19.2)	(12.0)	(14.7)	(15.9)	0.100 b
C	316	47	42	95	522	106
	(80.6)	(73.4)	(80.8)	(88.0)	(85.3)	(84.1)
G/G	128	19	17	43	222	44	0.079 a
	(65.3)	(59.4)	(65.4)	(79.6)	(72.5)	(69.8)	0.054 b
G/C	60	9	8	9	78	18
	(30.6)	(28.1)	(30.8)	(16.7)	(25.5)	(28.6)
C/C	8	4	1	2	6	1
	(4.1)	(12.5)	(3.8)	(3.7)	(2.0)	(1.6)

^aComparisons among healthy individuals and the five groups of different severity of goiter.

^bComparisons among the five groups of different severity of goiter.