Table 4. Odds ratios of severity of goiter cases categorized by MIF polymorphism rs755622 in patients with untreated Graves disease.

	Comparison to Healthy				Comparison to Grave disease, goiter grade 0
Polymorphisms		OR	95%CI	P value		OR	95%CI	P value
G	H vs 0	1.000		0.001
C		5.821	1.978–18.843
G/G		1.000		0.002
G/C		6.400	0.652–62.812
C/C		32.000	2.615–391.587
G	H vs 1a	1.000		0.579	0 vs 1a	1.000		0.074
C		1.386	0.435–4.417			0.238	0.048–1.193
G/G		1.000		0.466		1.000		0.155
G/C		2.133	0.516–8.821			0.333	0.023–4.736
C/C		0.000	0.000–			0.000	0.000–
G	H vs 1b	1.000		0.577	0 vs 1b	1.000		0.003
C		0.787	0.338–1.833			0.135	0.033–0.550
G/G		1.000		0.745		1.000		0.026
G/C		0.667	0.233–1.905			0.104	0.009–1.239
C/C		1.000	0.117–8.524			0.031	0.001–0.720
G	H vs 2	1.000		0.221	0 vs 2	1.000		1.417×10−4
C		0.773	0.511–1.169			0.133	0.040–0.438
G/G		1.000		0.458		1.000		7.072×10−5
G/C		0.808	0.495–1.321			0.126	0.013–1.254
C/C		0.505	0.131–1.955			0.016	0.001–0.226
G	H vs 3	1.000		0.215	0 vs 3	1.000		3.661×10−4
C		0.594	0.259–1.363			0.102	0.025–0.411
G/G		1.000		0.417		1.000		0.002
G/C		0.711	0.287–1.764			0.111	0.010–1.249
C/C		0.000	0.000-			0.000	0.000-

Abbreviations: MIF, macrophage migration inhibitory factor; OR, odd ratio; CI, confidence interval.