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. 2014 Mar 25;9(3):e92912. doi: 10.1371/journal.pone.0092912

Figure 5. Oral administration of BV modulated GSK3β and Foxp3 expression in the pulmonary tissues of asthmatic mice models.

Figure 5

(A), Representative immunohistochemical results of GSK3β and Foxp3 expression in the pulmonary tissues of asthmatic mice models (magnification ×400). (B), Oral administration of BV significantly decreased the ratio of GSK3β+ cells, but increased the ratio of Foxp3+ cells, in the pulmonary tissues of asthmatic mice models in 2 monBV/OVA/OVA group, as indicated by integrated optical density (n = 6). (C), The mRNA expression levels of GSK3β and Foxp3 were showed by RT-QPCR, when normalized by GAPDH and compared with PBS/PBS/PBS group. Each sample was tested for 3 times and averaged, all values were expressed as mean ± SD. * P<0.05.