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. 2013 Apr 2;19(4):471–477. doi: 10.1038/mp.2013.31

Table 1. Meta-analyses of categorical studies of genetic associations with aggression.

Gene N OR 95% CI P-value p(Q) I2(%) 95% CI
HTR1B 5 0.86 0.60–1.23 0.42 0.06 56 0–83
5HTTLPR 19 0.90 0.74–1.09 0.29 0 66 45–79
5HTT-VNTR 3 1.18 0.89–1.58 0.26 0.80 0 0–53
BDNF 4 0.86 0.65–1.13 0.27 0.20 35 0–77
COMT 19 0.84 0.63–1.02 0.08 0 64 41–78
SLC6A3a 3 1.19 0.91–1.56 0.20 0.92 0 0
DRD4a 4 1.40 0.87–2.26 0.17 0.09 53 0–85
MAOA-F 5 0.96 0.64–1.45 0.86 0.33 13 0–82
MAOA-M 17 0.82 0.65–1.05 0.13 0.01 50 13–71
TPH1 5 1.19 0.92–1.54 0.18 0.05 58 0–84
AR (CAG) 3 3.04 0.94–9.84 0.06 0 91 76–97
DRD2 3 1.30 0.99–1.71 0.06 0.26 25 0–92

Abbreviations: CI, confidence interval; I, I2 test for heterogeneity; MAOA-F and MAOA-M, MAOA in females and males, respectively; N, number of studies included; OR, pooled odds ratio; p(Q), P-value of Cochran's Q test for heterogeneity.

a

Genotypic analysis of the dominant model for SLC6A3 and DRD4.