Table 2.
EEG and physiology during FDG infusion compared with animal physiology before FDG infusion. Data represent average of 4 recordings using two tailed Student’s t-test analysis. EEG data were processed in terms of root mean square to reflect the power. fMRI activation for each dose is indicated.
| FDG dose (mg/kg) | parameter measured | no FDG infusion | with FDG infusion | p value | fMRI activation |
|---|---|---|---|---|---|
| 60 | blood pressure | 90±14 | 92±14 | 0.42 | observed, data not shown |
| respiration rate | 2.6±0.1 | 2.6±0.1 | 0.92 | observed, data not shown | |
| EEG | 0.28±0.04 | 0.26±0.04 | 0.09 | observed, data not shown | |
| 500 | blood pressure | 97±15 | 98±19 | 0.57 | observed, see Fig. 3 |
| respiration rate | 2.6±0.1 | 2.6±0.1 | 0.99 | observed, see Fig. 3 | |
| EEG | 0.17±0.04 | 0.19±0.04 | 0.22 | observed, see Fig. 3 | |
| 800 | blood pressure | 98±21 | 90±20 | 0.002 | not observed, data not shown |
| respiration rate | 2.6±0.1 | 2.6±0.1 | 0.19 | not observed, data not shown | |
| EEG | 0.20±0.04 | 0.14±0.04 | <0.001 | not observed, data not shown |