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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Neuroimage. 2014 Jan 10;91:237–251. doi: 10.1016/j.neuroimage.2013.12.067

Fig. 5. Reproducibility of BOLD and CBVw activation maps to 5% amyl acetate by comparing even and odd fMRI runs.

Fig. 5

Three center slices from a single representative animal are shown. A–B: Statistical t-value maps of even and odd runs are qualitatively similar for both BOLD and CBVw fMRI. However, across techniques, the sensitivity increase of CBVw is apparent by the increased number of hot pixels. C–D: Even and odd maps with thresholds of t > 4 and t > 2 were overlapped, where activation from only even runs is in green, only odd runs in yellow and common activation in red. The SCC values for these particular images are displayed in the lower right corners. E: SCC values were calculated across 5 animals to quantitatively evaluate reproducibility (even ∩ odd). All SCC values are above 0.2, indicating significant overlap (p < 0.01) and good reproducibility for both BOLD and CBVw maps. In addition, CBVw fMRI had significantly greater reproducibility compared to BOLD in GL at the higher threshold (* p < 0.05, paired Student’s t-test, n = 5).