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. Author manuscript; available in PMC: 2015 Mar 28.
Published in final edited form as: Life Sci. 2014 Feb 2;100(1):25–34. doi: 10.1016/j.lfs.2014.01.072

Fig. 2.

Fig. 2

EGFR transactivation. The ability of 100 nM NTS and 0.5 µg/ml SR48692 to alter EGFR tyrosine phosphorylation of Tyr1068 was investigated in untreated NCI-H1299 cells (A) and siRNA-NTSR1 treated NCI-H1299 (B) cells. As controls, total EGFR and tubulin were not affected by siRNA-NTSR1. The mean value ± S.D. of 3 determinations is indicated using NCI-H1299 untreated cells (E) and cells treated with siRNA-NTSR1 (F); p < 0.01, **; p < 0.05, * relative to Lane 1, p < 0.05, a relative to lane 2. The ability of 100 nM NTS and 0.5 µg/ml SR48692 to alter EGFR tyrosine phosphorylation of Tyr1068 was investigated in untreated NCI-A549 cells (C) and siRNA-NTSR1 treated A549 (D) cells was investigated. As controls, total EGFR and tubulin are provided. The mean value ± S.D. of 3 determinations is indicated using A549 untreated cells (G) and cells treated with siRNA-NTSR1 (H); p < 0.01, **; p < 0.05, * relative to Lane 1, p < 0.05, a relative to lane 2 by ANOVA.