Figure 5. Influenza infection inhibits NADPH oxidase-dependent bacterial killing.
(A) Numbers of bacteria (4–8 mice/group) in the lungs, and (B) airway inflammatory cell accumulation at 24 h after infection WT and gp91phox−/− mice (n=4) with 107 CFU of MRSA BAA-1695 alone (MRSA) or on day 7 after PR8 infection (Flu + MRSA). In (A&B), P<0.001, ANOVA; *P< 0.05, ***P< 0.001, Tukey’s multiple comparisons test.