Table 1.
Clinicopathologic data for 1,000 patients undergoing CS and HIPEC for peritoneal surface disease
| 1st quintile | 2nd | 3rd | 4th | 5th | ||
|---|---|---|---|---|---|---|
| Primary (n) | ||||||
| Appendix (472) | 56 (28%) | 80 (40%) | 116 (58%) | 121 (60.5%) | 99 (49.5%) | |
| Colon (232) | 58 (29%) | 50 (25%) | 40 (20%) | 40 (20%) | 44 (22%) | |
| Gastric (46) | 27 (13.5%) | 12 (6%) | 3 (1.5%) | 2 (1%) | 2 (1%) | |
| Mesothelioma (72) | 12 (6%) | 13 (6.5%) | 12 (6%) | 12 (6%) | 23 (11.5%) | |
| Ovary (69) | 18 (9%) | 25 (12.5%) | 5 (2.5%) | 8 (4%) | 13 (6.5%) | |
| Others (109) | 29 (14.5%) | 20 (10%) | 24 (12%) | 17 (8.5%) | 19 (9.5%) | |
| Complications | P<0.0001 | |||||
| No (N=422) | 92 (46%) | 76 (38%) | 49 (24%) | 90 (45%) | 115 (58%) | |
| Yes (N=578) | 108 (54%) | 124 (62%) | 151 (76%) | 110 (55%) | 85 (42%) | |
| Transfusion | ||||||
| No | 80 (45.2%) | 104 (68.9%) | 129 (68.3%) | 129 (65.2%) | 149 (76.8%) | |
| Yes | 97 (54.8%) | 47 (31.1%) | 60 (31.7%) | 69 (34.8%) | 45 (23.2%) | |
| Stoma | p=0.001 | |||||
| No | 160 (88.4%) | 141 (70.5%) | 160 (80.0%) | 159 (79.5%) | 193 (96.5%) | |
| Colostomy | 15 (8.3%) | 28 (14.0%) | 8 (4.0%) | 14 (7.0%) | 7 (3.5%) | |
| Ileostomy | 6 (3.3%) | 31 (15.5%) | 32 (16.0%) | 27 (13.5%) | 22 (11.0%) | |
| ECOG | P<0.0001 | |||||
| 0 | 53 (26.8%) | 84 (42.0%) | 85 (42.5%) | 115 (59.0%) | 105 (54.7%) | |
| 1 | 99 (50.0%) | 86 (43.0%) | 82 (41.0%) | 57 (29.2%) | 64 (33.3%) | |
| 2 | 36 (18.2%) | 22 (11.0%) | 28 (14.0%) | 19 (9.7%) | 16 (8.3%) | |
| 3 or 4 | 10 (5.1%) | 8 (4.0%) | 5 (2.5%) | 4 (2.1%) | 7 (3.7%) | |
| Resection | P<0.0001 | |||||
| R0/R1 | 71 (35.5%) | 93 (46.5%) | 103 (51.8%) | 93 (46.5%) | 104 (52.8%) | |
| R2a | 39 (19.5%) | 55 (27.5%) | 49 (24.6%) | 73 (36.5%) | 69 (35.0%) | |
| R2b | 31 (15.5%) | 32 (16.0%) | 34 (17.1%) | 28 (14.0%) | 15 (7.6%) | |
| R2c | 59 (29.5%) | 20 (10.0%) | 13 (6.5%) | 6 (3.0%) | 9 (4.6%) | |
| Clavien- Dindo | 1st quintile | 2nd | 3rd | 4th | 5th | P<0.003 |
| 0 | 59 (30.6%) | 72 (36.0%) | 59 (29.5%) | 65 (32.5%) | 39 (29.8%) | |
| I | 11 (5.2%) | 11 (5.5%) | 13 (6.5%) | 31 (15.5%) | 16 (12.2%) | |
| II | 75 (38.9%) | 54 (27.0%) | 53 (26.5%) | 51 (25.5%) | 35 (26.7%) | |
| III | 27 (14.0%) | 34 (17.0%) | 49 (24.5%) | 33 (16.5%) | 23 (17.6%) | |
| IV | 14 (7.2%) | 17 (8.5%) | 21 (10.5%) | 12 (6.0%) | 13 (9.9%) | |
| V | 8 (3.1%) | 12 (6.0%) | 5 (2.5%) | 8 (4.0%) | 5 (3.8%) | |
| Hospital LOS | median 9 | 9 | 10 | 9 | 8 | p=0.03 |
| ICU LOS | 2 | 2 | 1 | 1 | 1 | P<0.0001 |
| Pre HIPEC Chemo | ||||||
| No | 59 (36%) | 122 (61%) | 107 (54%) | 85 (42%) | 48 (32%) | |
| Yes | 105 (64%) | 77 (39%) | 93 (46%) | 115 (58%) | 100 (68%) |