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Cardiovascular effects as a function of time (min) in Experiment 2. Open symbols indicate changes from baseline heart rate as beats per min (BPM), and closed symbols indicate changes from baseline blood pressure as mean arterial pressure (MAP) every 10 s following histamine, saline, and the antagonists prior to saline (left side) or prior to histamine (right side). Pretreatment type is indicated in the left side. Error bars are SEM.
