Table 2.
Number of intranuclear inclusions (counts and percent) in neaurons and asytrocytes.
| A. Cortex
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Subject | Gray Matter
|
White Matter
|
||||||
| Neurons | % | Astrocytes | % | Neurons | % | Astrocytes | % | |
| Case 1 | 24/265 | 9.06 | 25/680 | 3.68 | 3/26 | 11.54 | 30/346 | 8.67 |
| Case 2 | 16/190 | 8.40 | 2/117 | 1.80 | 1/57 | 1.75 | 21/615 | 3.41 |
| Case 3 | 2/231 | 0.80 | 5/200 | 2.50 | 3/5 | 60.00 | 19/333 | 5.71 |
| Case 4 | 0/370 | 0.00 | 14/504 | 2.80 | 6/19 | 31.58 | 12/662 | 1.81 |
| Case 5 | 6/251 | 0.02 | 10/403 | 0.02 | 1/7 | 0.14 | 9/501 | 0.02 |
| Case 6 | 62/456 | 13.60 | 240/1729 | 13.90 | 6/56 | 10.70 | 38/333 | 11.40 |
| Case 7 | 18/221 | 8.14 | 21/746 | 2.82 | 2/28 | 7.14 | 23/552 | 4.17 |
| Case 8 | 17/358 | 4.75 | 45/701 | 6.42 | 9/77 | 11.69 | 23/299 | 7.69 |
|
| ||||||||
| Mean | -- | 5.6 | -- | 4.24 | -- | 16.8 | -- | 5.36 |
| Controls | 0/361 | 0 | 0/251 | 0 | 0/16 | 0 | 0/303 | 0 |
| B. Hippocampus | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||||
| Subject | Pyramidal Cell Layer (CA1–CA3)
|
Granule Cell Layer (DG)
|
Hilus
|
Superior Medial Temporal Gyrus
|
||||||||||||
| Neurons | % | Astrocytes | % | Neurons | % | Astrocytes | % | Neurons | % | Astrocytes | % | Neurons | % | Astrocytes | % | |
| Case 1 | 11/361 | 3.05 | 38/496 | 7.66 | 43/766 | 5.61 | 13/90 | 14.44 | 6/249 | 2.41 | 23/537 | 4.66 | 27/384 | 6.77 | 54/684 | 7.89 |
| Case 2 | 1/118 | 0.90 | 9/75 | 12.00 | 3/260 | 1.20 | 1/12 | 8.30 | 0/97 | 0.00 | 15/109 | 13.80 | -- | -- | ||
| Case 3 | 7/148 | 4.70 | 4/127 | 3.10 | 6/372 | 1.70 | 2/10 | 20.00 | 11/100 | 11.00 | 17/117 | 14.50 | 25/347 | 6.94 | 44/754 | 5.84 |
| Case 4 | 0/538 | 0.00 | 0/239 | 0.00 | 0/1094 | 0.00 | 0/85 | 0.00 | 0/251 | 0.00 | 0/462 | 0.00 | 26/298 | 8.72 | 82/730 | 11.23 |
| Case 5 | 8/289 | 2.77 | 17/364 | 4.67 | 28/806 | 3.47 | 17/199 | 4.26 | 3/155 | 1.94 | 6/332 | 1.81 | 16/316 | 5.06 | 44/326 | 6.06 |
| Case 6 | 79/332 | 24.00 | 157/698 | 22.00 | 100/899 | 11.00 | 12/46 | 26.00 | 97/265 | 37.00 | 205/831 | 25.00 | 46/234 | 20.00 | 146/774 | 19.00 |
| Case 7 | 36/486 | 7.41 | 9/123 | 7.32 | 27/486 | 5.56 | 13/107 | 12.15 | 14/160 | 8.75 | 14/209 | 6.70 | 20/297 | 6.73 | 61/599 | 10.18 |
| Case 8 | 26/263 | 9.89 | 72/514 | 14.01 | 68/777 | 8.75 | 6/82 | 7.32 | 54/305 | 17.70 | 101/901 | 11.21 | 52/236 | 22.03 | 50/722 | 6.93 |
|
| ||||||||||||||||
| Mean | -- | 6.59 | -- | 8.84 | -- | 4.66 | -- | 11.56 | -- | 9.85 | -- | 9.71 | -- | 11.59 | -- | 9.49 |
| Controls | 0/109 | 0.00 | 0/165 | 0.00 | 0/483 | 0.00 | 0/45 | 0.00 | 0/110 | 0.00 | 0/280 | 0.00 | ||||