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. 2014 Mar 26;34(13):4599–4607. doi: 10.1523/JNEUROSCI.4923-13.2014

Figure 4.

Figure 4.

Age-related threshold shift was more pronounced in de-efferented regions, especially as measured via ABRs. A, B, Mean threshold shift (±SEM) vs age for Control vs OC Lesion groups, as seen via DPOAEs (A) or ABRs (B). Data from each group are averaged across all test frequencies. C, D, Mean cochlear threshold shift (±SEM) vs frequency for Control vs OC Lesion groups as seen via DPOAEs (C) or ABRs (D). For DPOAEs, differences between the OC Lesion group at 45 weeks and age-matched controls were significant at the p ≪ 0.01 level for 11.3, 16, 22.6, and 32 kHz; differences at 45.2 kHz were significant at the p < 0.05 level. For ABRs, differences were significant at the p < 0.01 level for 5.6, 8, 22.6, and 32 kHz, and at the p < 0.05 level for 11.3, 16, and 45.2 kHz. All data are normalized to the mean values for each group at 8 weeks. OC Lesion group is defined as shown in Figure 3A. Group sizes are as described in Figure 3.