TABLE 2.
Disease parameters
Impact of C. rodentium infection on total body and relative organ weight of liver and spleen, as well as bacterial load in colon, blood, and liver. Values are mean ± S.E.M. (n = 6): body weight at sacrifice relative to body weight preinfection; organ weight at sacrifice relative to body weight at sacrifice; bacterial CFU per gram of tissue or per 50 μl of blood.
| HeOuJ |
HeJ |
|||
|---|---|---|---|---|
| Control | Infected | Control | Infected | |
| Body weight | 1.035 ± 0.009 | 0.921 ± 0.024* | 1.009 ± 0.009 | 0.886 ± 0.026* |
| Liver (% body weight) | 5.13 ± 0.16 | 5.21 ± 0.13 | 4.98 ± 0.08 | 5.13 ± 0.28 |
| Spleen (% body weight) | 0.466 ± 0.023 | 0.933 ± 0.137* | 0.539 ± 0.027 | 1.126 ± 0.078* |
| Colon bacterial CFU (×105) | n.a. | 1049.7 ± 250.0 | n.a. | 1451.2 ± 340.5 |
| Blood bacterial CFU | n.a. | 179.8 ± 164.1 | n.a. | 116.3 ± 35.5 |
| Liver bacterial CFU | n.a. | 441.7 ± 147.0 | n.a. | 4868.2 ± 2773.9 |
*
Significantly different than control, P < 0.05; n.a., not applicable.