TABLE 2.
Correlation between UGT2B mRNA expression levels in different tissuesa
| UGT2B4 | UGT2B7 | UGT2B10 | UGT2B11 | UGT2B15 | UGT2B17 | |
|---|---|---|---|---|---|---|
| Liver | ||||||
| UGT2B4 | 0.74**** | 0.73**** | −0.25 | 0.70**** | 0.05 | |
| UGT2B7 | 0.94**** | −0.25 | 0.82**** | 0.21 | ||
| UGT2B10 | −0.14 | 0.84**** | −0.08 | |||
| UGT2B11 | −0.17 | 0.06 | ||||
| UGT2B15 | −0.06 | |||||
| UGT2B17 |
||||||
| Lung | ||||||
| UGT2B4 | 0.19 | 0.18 | 0.34 | 0.34 | 0.39 | |
| UGT2B7 | 0.93**** | 0.98**** | 0.98**** | 0.87** | ||
| UGT2B10 | 0.95**** | 0.97**** | 0.93**** | |||
| UGT2B11 | 0.87*** | 0.45 | ||||
| UGT2B15 | 0.80** | |||||
| UGT2B17 |
||||||
| Larynx | ||||||
| UGT2B4 | N/A | 0.97** | 0.96** | 0.99*** | 0.86* | |
| UGT2B7 | N/A | N/A | N/A | N/A | ||
| UGT2B10 | 0.96** | 0.99**** | 0.90* | |||
| UGT2B11 | 0.97** | 0.90* | ||||
| UGT2B15 | 0.89* | |||||
| UGT2B17 |
||||||
| Esophagus | ||||||
| UGT2B4 | N/A | 0.96**** | 0.94**** | −0.19 | 0.87*** | |
| UGT2B7 | N/A | N/A | N/A | N/A | ||
| UGT2B10 | 0.92*** | −0.21 | 0.86** | |||
| UGT2B11 | −0.07 | 0.91**** | ||||
| UGT2B15 | −0.11 | |||||
| UGT2B17 |
||||||
| Tonsil | ||||||
| UGT2B4 | N/A | 0.99**** | 0.99**** | 0.99**** | 0.79**** | |
| UGT2B7 | N/A | N/A | N/A | N/A | ||
| UGT2B10 | 0.98**** | 0.99**** | 0.75**** | |||
| UGT2B11 | 0.99**** | 0.82**** | ||||
| UGT2B15 | 0.83**** | |||||
| UGT2B17 |
||||||
| Pancreas | ||||||
| UGT2B4 | −0.17 | 0.42 | −0.05 | −0.19 | −0.40 | |
| UGT2B7 | −0.95** | 0.28 | 0.20 | −0.06 | ||
| UGT2B10 | 0.72 | −0.52 | −0.86 | |||
| UGT2B11 | 0.17 | −0.25 | ||||
| UGT2B15 | 0.04 | |||||
| UGT2B17 |
*
p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
a
Data presented are r2 values from correlation analyses of expressed isoforms using the Spearman’s rank method.