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. Author manuscript; available in PMC: 2015 Feb 14.
Published in final edited form as: Circ Res. 2013 Dec 3;114(4):660–671. doi: 10.1161/CIRCRESAHA.114.302931

Figure 3. Introgression of Dce1 into the Bc genome rescues blood flow after middle cerebral artery occlusion (MCAO).

Figure 3

24 hr after permanent MCAO, relative blood flow in the volume of infarcted brain and corresponding contralateral region (used for normalization) were determined using the microsphere method after maximal dilation. Relative blood flow was 4.5-fold greater in CNG4-B6/B6 compared to CNG4-Bc/Bc. Insets: Robust collateral-dependent retrograde perfusion in CNG4-B6/B6 is indicated by minimal brown clotted blood in the MCA territory, compared to the clearly visible brown tracks in the CNG-Bc/Bc brain. Baseline flow (non-ligated side) did not differ between strains.