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. Author manuscript; available in PMC: 2015 Feb 14.
Published in final edited form as: Circ Res. 2013 Dec 3;114(4):660–671. doi: 10.1161/CIRCRESAHA.114.302931

Figure 6. Haplotype, gene and SNP distribution in Dce1.

Figure 6

A, Haplotype maps of B6 and Bc in Dce1 from the Mouse Phylogeny Viewer.66 Three haplotype blocks contain 11 of the 28 genes and 15 of the 27 candidate SNPs in Dce1 that distinguish Bc from B6. B, Genes within Dce1 that are involved in vascular biology, harbor candidate SNPs, or occur in haplotype blocks. Rabep2, the only gene in all 3 categories, contains 7 candidate SNPs (5 intronic, one synonymous, one non-synonymous) and lies in the small haplotype block number 2 (73 kb) in which lie half of the candidate SNPs in Dce1. Numbers in parentheses indicate the number of candidate SNPs in each block. C, All SNPs (red bars) and candidate SNPs (black) are unevenly distributed in Dce1.