Table 4. Mean metabolite estimated precision (%CRLB) by group for each of four metabolites in three voxels.
| Control mean (s.d.) |
ADHD |
P-value | |||
|---|---|---|---|---|---|
| Total | Medicated | Not medicated | |||
| mean (s.d.) | mean (s.d.) | mean (s.d.) | |||
| Basal ganglia | |||||
| Cho | 0.095 (0.026) | 0.097 (0.027) | 0.089 (0.018) | 0.104 (0.032) | 0.279 |
| Cr | 0.071 (0.019) | 0.071 (0.014) | 0.068 (0.009) | 0.073 (0.016) | 0.581 |
| NAA | 0.100 (0.028) | 0.109 (0.023) | 0.106 (0.022) | 0.111 (0.025) | 0.393 |
| Glx | 0.097 (0.04) | 0.100 (0.044) | 0.086 (0.012) | 0.111 (0.056) | 0.194 |
| DLPFC | |||||
| Cho | 0.075 (0.018) | 0.067 (0.011) | 0.068 (0.012) | 0.066 (0.011) | 0.161 |
| Cr | 0.067 (0.013) | 0.061 (0.008) | 0.063 (0.009) | 0.06 (0.008) | 0.120 |
| NAA | 0.072 (0.017) | 0.067 (0.012) | 0.067 (0.011) | 0.067 (0.013) | 0.456 |
| Glx | 0.144 (0.056) | 0.103 (0.033) | 0.099 (0.033) | 0.105 (0.034) | 0.004 |
| Parietal cortex | |||||
| Cho | 0.089 (0.015) | 0.091 (0.015) | 0.093 (0.016) | 0.090 (0.015) | 0.654 |
| Cr | 0.066 (0.012) | 0.065 (0.01) | 0.068 (0.012) | 0.063 (0.009) | 0.511 |
| NAA | 0.072 (0.012) | 0.075 (0.015) | 0.076 (0.017) | 0.074 (0.014) | 0.671 |
| Glx | 0.092 (0.02) | 0.101 (0.042) | 0.095 (0.023) | 0.105 (0.053) | 0.488 |
Abbreviations: ADHD, attention-deficit hyperactivity disorder; Cho, choline; Cr, creatine; %CRLB, % Cramer–Rao Lower Bounds; DLPFC, dorsolateral predfrontal cortex; Glx, glutamate and glutamine; NAA, N-acetylaspartate.
Data are given as mean (s.d.). P-value: two-tailed t-test for analysis of variance comparing control; ADHD medicated and ADHD naive groups by %CRLB.