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. 2014 Mar 18;4(3):e373. doi: 10.1038/tp.2014.11

Table 4. Mean metabolite estimated precision (%CRLB) by group for each of four metabolites in three voxels.

  Control mean (s.d.) ADHD
P-value
    Total Medicated Not medicated  
    mean (s.d.) mean (s.d.) mean (s.d.)  
Basal ganglia
 Cho 0.095 (0.026) 0.097 (0.027) 0.089 (0.018) 0.104 (0.032) 0.279
 Cr 0.071 (0.019) 0.071 (0.014) 0.068 (0.009) 0.073 (0.016) 0.581
 NAA 0.100 (0.028) 0.109 (0.023) 0.106 (0.022) 0.111 (0.025) 0.393
 Glx 0.097 (0.04) 0.100 (0.044) 0.086 (0.012) 0.111 (0.056) 0.194
DLPFC
 Cho 0.075 (0.018) 0.067 (0.011) 0.068 (0.012) 0.066 (0.011) 0.161
 Cr 0.067 (0.013) 0.061 (0.008) 0.063 (0.009) 0.06 (0.008) 0.120
 NAA 0.072 (0.017) 0.067 (0.012) 0.067 (0.011) 0.067 (0.013) 0.456
 Glx 0.144 (0.056) 0.103 (0.033) 0.099 (0.033) 0.105 (0.034) 0.004
Parietal cortex
 Cho 0.089 (0.015) 0.091 (0.015) 0.093 (0.016) 0.090 (0.015) 0.654
 Cr 0.066 (0.012) 0.065 (0.01) 0.068 (0.012) 0.063 (0.009) 0.511
 NAA 0.072 (0.012) 0.075 (0.015) 0.076 (0.017) 0.074 (0.014) 0.671
 Glx 0.092 (0.02) 0.101 (0.042) 0.095 (0.023) 0.105 (0.053) 0.488

Abbreviations: ADHD, attention-deficit hyperactivity disorder; Cho, choline; Cr, creatine; %CRLB, % Cramer–Rao Lower Bounds; DLPFC, dorsolateral predfrontal cortex; Glx, glutamate and glutamine; NAA, N-acetylaspartate.

Data are given as mean (s.d.). P-value: two-tailed t-test for analysis of variance comparing control; ADHD medicated and ADHD naive groups by %CRLB.