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A. Replicative lifespan of isogenic strains that are wild type (“WT”) or carrying an extra copy of either HHT2/HHF2 or HTB1/HTA1 driven from the galactose inducible pGAL1/10 divergent promoter integrated into the genome grown on 1% galactose and B. on 2% galactose. C. Model for lifespan extension by increasing histone supply.
