Table 1.
Cytokine | 0 | a25 | 50 | 100 | 200 | 100 b TiO2 |
---|---|---|---|---|---|---|
IL-1β | c 1.00 | d 3.10 ± 2.70 | 1.00 ± 0.65 | 1.42 ± 0.82 | 1.49 ± 0.27 | 4.90 ± 1.55 |
IL-2 | 1.00 | 1.87 ± 1.08 | 1.67 ± 0.37 | 1.60 ± 0.99 | 1.62 ± 0.31 | 1.67 ± 0.84 |
IL-4 | 1.00 | 2.08 ± 3.61 | 2.01 ± 1.81 | 2.05 ± 2.88 | 2.71 ± 2.78 | 12.2 ± 13.6 |
IL-5 | 1.00 | 1.20 ± 1.02 | 0.92 ± 0.05 | 0.79 ± 0.43 | 0.83 ± 0.40 | 2.52 ± 0.62 |
IL-8 | 1.00 | 1.73 ± 0.44 | 1.54 ± 0.39 | 1.54 ± 0.15 | 2.42 ± 0.03 | 2.33 ± 0.39 |
IL-10 | 1.00 | 1.69 ± 0.88 | 1.77 ± 0.62 | 2.16 ± 0.31 | 2.02 ± 0.63 | 2.51 ± 0.44 |
IL-12 | 1.00 | 0.00 ± 0.00 | 0.95 ± 0.86 | 1.89 ± 0.00 | 3.58 ± 0.84 | 7.58 ± 5.06 |
IL-13 | 1.00 | 1.48 ± 0.75 | 0.83 ± 0.52 | 1.13 ± 0.48 | 1.29 ± 0.43 | 1.54 ± 0.75 |
TNF-α | 1.00 | 0.88 ± 0.59 | 0.64 ± 0.39 | 1.55 ± 1.03 | 1.88 ± 1.07 | 2.30 ± 1.25 |
IFN-γ | 1.00 | 0.29 ± 0.44 | 0.12 ± 0.18 | 0.36 ± 0.33 | 0.51 ± 0.18 | 1.22 ± 0.96 |
Level of WTC2.5 (as μg/ml) used in the 5-hr exposure.
μg/ml used in the 5-hr exposure.
Value set to 1.00 for purposes of expressing relative change in cytokine level vs. that in unexposed control cultures.
Value is unit-less as it is calculated as relative change in levels (expressed here as mean relative cytokine level vs. that in unexposed control cultures [±SD]).