Figure 6. Subcurative irradiation increased the number of invasive cells positive for CD44.
A, immunohistochemical study shows presence of CD44-positive cells in the tumor and in the adjacent brain. Irradiation caused an increase in the foci of CD44-positive areas (black arrow; magnification 2×, 10×, and 40×). B, graphic representation shows a significant increase in the distance traveled by CD44-positive cells in irradiated tumors. *, P < 0.05.