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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Hypertension. 2014 Jan 27;63(3):e33–e39. doi: 10.1161/HYPERTENSIONAHA.113.02444

Figure 2.

Figure 2

Components of Ca2+ signaling in arterial smooth muscle that participate in the contractile process. The extracellular concentration of free Ca2+ is approximately 1.6 mmol/L whereas the intracellular concentration of the cation is 10,000-fold less (50-100 nmol/L). Abbreviations: adenosine triphosphate (ATP); diacylglycerol (DAG); guanine nucleotide exchange factor (GEF); guanosine diphosphate (GDP); guanosine triphosphate (GTP); inositol trisphosphate (IP3); IP3 receptor (IP3R); phosphoinosite phospholipase C (PLC); phosphatidylinositol 4,5-bisphosphate (PIP2); protein kinase C (PKC); stromal interaction molecule (STIM).