TABLE 2.
Perinatal, Demographic, and Hormone Characteristics
| 7-Year Cognitive Group (n = 83)a | 7-Year Imaging Group (n = 52)a | |
|---|---|---|
| Child characteristics | ||
| GA (wk), M (SD) | 27.3 (1.7) | 27.4 (1.6) |
| Birth weight (g), M (SD) | 975 (235) | 992 (216) |
| Males, n (%) | 35 (42.2) | 19 (36.5) |
| Singleton, n (%) | 49 (59.0) | 27 (51.9) |
| Perinatal medical factors | ||
| Small for GA, n (%) | 2 (2.4) | 2 (3.8) |
| Sepsis, n (%) | 34 (41.0) | 21 (40.4) |
| Patent ductus arteriosus, n (%) | 40 (48.2) | 23 (44.2) |
| Necrotizing enterocolitis, n (%) | 9 (10.8) | 4 (7.8) |
| Bronchopulmonary dysplasia, n (%) | 26 (31.7) | 15 (28.8) |
| Antenatal corticosteroids, n (%) | 76 (91.6) | 50 (96.2) |
| Postnatal corticosteroids, n (%) | 10 (12.0) | 4 (7.7) |
| IPPV (hours), median (25th and 75th percentile) | 98 (7, 431) | 88 (9, 376.5) |
| Cystic periventricular leukomalacia, n (%) | 1 (1.2) | 1 (1.9) |
| Grade III/IV intracentricular hemorrhage, n (%) | 3 (3.6) | 1 (1.9) |
| MRI brain injury, median (25th and 75th percentile) | 5 (3, 8) | 5 (3, 8) |
| Neonatal free thyroxine characteristics | ||
| 14-day AUC (pmol) | 154.1 (47.7) | 159.9 (46.8) |
| 42-day AUC (pmol) | 525.4 (114.4) | 535.0 (117.0) |
| 7-year measures | ||
| Social risk score at age 7 years, median (25th and 75th percentile) | 2 (1, 3) | 2 (0, 3) |
| FSIQ, M (SD) | 95.5 (17.8) | 99.5 (12.7)b |
a
Some sample sizes are less than the total sample owing to missing data.
b
Those in the image analysis group had higher FSIQs at age 7 years than those without imaging data (P = .007).