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. Author manuscript; available in PMC: 2014 Mar 26.
Published in final edited form as: Compr Physiol. 2013 Apr;3(2):667–692. doi: 10.1002/cphy.c110014

Figure 3.

Figure 3

Effects of CFTR gene knockout (FABPCFTR) on ischemic preconditioning in isolated working mouse heart. (A) Experimental protocol. (B–D) Recovery of left ventricular contractile (B and C.) and relaxation (D) function of wild-type WT (FVB/NJ), CFTR+/−, and CFTR−/− (FABPCFTR) mice after 45 min ischemia and 40 min reperfusion. (E) IPC on infarct size of ventricles. Representative ventricle transverse slices after ischemia (Isch) or IPC. (F). Mean infarct size measured from age-matched WT, CFTR+/−, or CFTR−/− mouse heart after ischemia or IPC (n = 6 for each group). *, P < 0.05; **, P < 0.01; ***, P < 0.001, NS: not significant (23). (Copyright Request: Chen H, et al. Circulation 110: 700–704, 2004.)