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. 2014 Feb 28;27(4):97–109. doi: 10.1093/protein/gzu002

Table III.

Binding kinetics and affinities determined by SPR for purified IgGs to VEGF

IgG kon (M−1 s−1) koff (s−1) KD (nM)
3A4 2.00 × 104 1.13 × 10−2 567
3C5 3.23 × 104 1.55 × 10−2 479
3D2 5.02 × 104 5.06 × 10−2 1010
3E3 2.09 × 104 1.45 × 10−3 69.3