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Measured molar binding constant for mutant (ERH) and native (WT) PrG against five IgG species.
|
Kd PrG-WT, (nM) |
Kd PrG-ERH, (nM) |
Affinity gain | Correlation coefficient | |
|---|---|---|---|---|
| Rabbit | 77 | 16 | 5x | 0.98 |
| Human | 250 | 49 | 5x | 0.94 |
| Goat | 320 | 300 | 1x | 0.97 |
| Rat | 670 | 1300 | 0.5x | 0.97 |
| Mouse | 920 | 640 | 1.5x | 0.99 |
