TABLE 1.
Available mouse strains for genetic manipulation of the adipose lineage
| Strain | Specificity | Expression in Adipose Lineage | Promoter |
| Fabp4-Cre (103), Fabp4-Cre (102), Fabp4-CreERT2 (123) | WAT and BAT. CNS, macrophages, endothelial cells, and cardiomyocytes (depending on strain) | Committed preadipocytes (some strains) and mature adipocytes | 5.4 kb |
| Adipo-Cre (110), Adipo-rtTA (73) | WAT, mosaic expression in BAT | Differentiating adipocytes, mature adipocytes | 5.4 kb |
| Adipo-Cre (23) | WAT and BAT | Differentiating adipocytes, mature adipocytes | BAC |
| Adipo-CreERT2 (124) | WAT, mosaic expression in BAT | Differentiating adipocytes, mature adipocytes | BAC |
| Resistin-Cre (107) | WAT and BAT. Some expression in CNS | Differentiating adipocytes, mature adipocytes | BAC, 33 kb fragment |
| Pparγ-tTA (37) | White and brown adipocytes, other tissues expressing Pparγ | Adipocyte progenitors and mature adipocytes | Knock-in endogenous allele |
| Ucp1-Cre (122), Ucp1-CreERT2 (98) | Beige and brown adipocytes | Mature adipocytes | BAC |
| Myf5-Cre (115) | Muscle lineage and brown adipocytes, mosaic expression in other cell types | Classical brown adipocyte precursors | Knock-in endogenous allele |
| Pax7-Cre (222), Pax7-CreERT2 (223) | Satellite cells and embryonic brown adipocyte precursors | Classical embryonic brown adipocyte precursors | Knock-in endogenous allele |