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. 2014 Apr;55(4):718–728. doi: 10.1194/jlr.M046151

Fig. 2.

Fig. 2.

Upregulation of lipogenic gene expression does not result in hepatic lipid accumulation in Elovl2−/− mice fed standard chow diet. Analysis of hepatic gene expression of SREBP-1c, FAS, and SCD1 (A) in wild-type and Elovl2−/− mice fed standard chow diet. nSREBP-1c protein expression in hepatic nuclear extracts from wild-type and Elovl2−/− animals fed standard chow diet (B). Microscopic overview (C) of liver tissue from wild-type and Elovl2−/− mice fed standard chow diet and content of neutral lipids and phospholipids (D). Time course showing REE (E) and mean values of respiratory quotient (RQ) (F) during a 22 h period for wild-type and Elovl2−/− mice fed standard chow diet. Results shown are means ± SEM of 3–6 mice (exception E and F). Statistical significances are shown between wild-type and Elovl2−/−. * P < 0.05, ** P < 0.01, and *** P < 0.001.