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. 2014 Mar 18;171(7):1642–1654. doi: 10.1111/bph.12504

Figure 7.

Figure 7

Blood glucose and insulin levels following OGTT in male gkwt/del mice on HF diet ± GKA71 and wild-type littermates on HF or chow diet after 49 weeks. (A) Glucose levels during OGTT. gkwt/del mice on HF diet alone (n = 10), HF diet + GKA71 at 2.5 mg·kg−1·day−1 (n = 7), HF diet + GKA71 at 5 mg·kg−1·day−1 (n = 10). Wild-type littermates on HF diet alone (n = 8), chow diet alone (n = 10). (B) Glucose AUC(0–90 min) values (mM·h). (C) Insulin levels during OGTT. (D) Insulin AUC(0–90 min) values (pM.h). Data are mean ± SEM. ***P < 0.001 versus gkwt/del mice on HF diet alone, †P < 0.05, versus wild-type on HF diet.