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Voiding frequency in SAMP8 and SAMR1 mice. The total and the small volume voids (≤0.5 cm) are expressed as the number of voids per hour in male and female SAMR1 and SAMP8 mice. The data are expressed as the mean ± SE (n = 27–28 per group): *P < 0.05, **P < 0.01 versus SAMR1; #P < 0.05, ##P < 0.01 versus female (anova followed by Student's t-test).
