Figure 4.

CSY0073 inhibits airway neutrophil recruitment induced by Pseudomonas aeruginosa LPS. Counts of (A) macrophages and (B) neutrophils 3 and 24 h after challenge with 100 μg·kg⁻¹ LPS or PBS. Mice were pretreated 2 h before the challenge with vehicle (V: DMSO), CSY0073 (CSY) or AZM. Data are mean ± SEM of 7–8 mice per group. Statistical analysis was done for each time point, 3 h (*) or 24 h (#), by use of anova followed by Bonferroni's multiple comparison test. ***P < 0.001 and ****P < 0.0001.