Figure 2. Confocal laser images of wild-type, G615V and C201F LDLR localization in transfected HEK-293 cells.
Cells were incubated with tetramethylrhodamine-conjugated concanavalin A at room temperature for 1 hour. Overlays are shown in the right panels with co-localization appearing yellow. Similar results were obtained in 3 separate experiments.