Figure 9. Relative expression of dorsal skin development-related genes in Wnt11 knock-out mice and wild-type.

A. At stage E12.5, Msx1 shows much less expression in mutant mice than wild-type mice. (***:P<0,001). B. At stage E16.5, Wnt11 expression in Wnt11 knock-out mice is undetectable compared to wild-type mice. Fgf10 has less expression in the homozygous mice. Twist1, Twist2 and Krt5 expression does not show significant differences between wild-type and homozygous animals.