. 2014 Mar 26;9(3):e92859. doi: 10.1371/journal.pone.0092859

Table 3. Logistic regression of presence of problems in mobility, self care and usual activities (EQ5D) and presence of anxiety and depression (HADS) by BMI tertiles and by continuous BMI.

		1^st tertile ( ≤ 42.99)	2^nd tertile (43.00 − 48.61)	3^rd tertile ( ≥ 48.62)	P for linear trend	Continuous BMI
		Odds ratio (95% CI)
Mobility problems	Univariate	1.00	1.25 (0.64 − 2.44)	2.95 (1.40 − 6.22)^*	0.004	1.07 (1.02 – 1.12)^*
	Model 1	1.00	1.32 (0.66 – 2.63)	2.83 (1.31 – 6.15)^*	0.008	1.07 (1.02 – 1.12)^*
	Model 2	1.00	1.64 (0.78 – 3.44)	3.44 (1.47 – 8.05)^*	0.009	1.08 (1.03 – 1.13)^*
Self care problems	Univariate	1.00	0.84 (0.41 – 1.72)	2.19 (1.09 – 4.39)^*	0.018	1.05 (1.01 – 1.09)^*
	Model 1	1.00	0.88 (0.42 – 1.88)	2.05 (0.98 – 4.27)	0.044	1.05 (1.01 – 1.10)^*
	Model 2	1.00	0.89 (0.41 – 1.96)	1.87 (0.86 – 4.09)	0.104	1.05 (1.00 – 1.09)^*
Problems performing usual activities	Univariate	1.00	1.71 (0.86 – 3.37)	2.65 (1.27 – 5.52)^*	0.008	1.05 (1.01 – 1.10)^*
	Model 1	1.00	1.73 (0.86 – 3.44)	2.48 (1.17 – 5.23)^*	0.016	1.05 (1.01 – 1.10)^*
	Model 2	1.00	2.04 (0.98 – 4.26)	2.45 (1.10 – 5.46)^*	0.040	1.05 (1.00 – 1.10)^*
Anxiety	Univariate	1.00	0.75 (0.37 – 1.51)	0.73 (0.36 – 1.45)	0.409	0.98 (0.95 – 1.02)
	Model 1	1.00	0.68 (0.33 – 1.42)	0.74 (0.35 – 1.54)	0.460	0.98 (0.94 – 1.01)
	Model 2	1.00	0.71 (0.34 – 1.50)	0.81 (0.37 – 1.74)	0.633	0.98 (0.95 – 1.02)
Depression	Univariate	1.00	1.57 (0.78 – 3.15)	1.00 (0.51 – 1.98)	0.958	1.00 (0.96 – 1.03)
	Model 1	1.00	1.59 (0.79 – 3.20)	1.06 (0.53 – 2.11)	0.910	1.00 (0.96 – 1.03)
	Model 2	1.00	1.65 (0.80 – 3.40)	1.26 (0.61 – 2.62)	0.550	1.00 (0.97 – 1.04)

Presence of problems defined as level 2 (some problems) and level 3 (extreme problems) scores on EQ5D-3L; Presence of anxiety and depression defined as HADS anxiety subscale score ≥8.

* P<0.05.

**P<0.001.

Model 1 adjusting for age and sex.

Model 2 additionally adjusting for diabetes, hypertension, arthritis, obstructive sleep apnoea, cardiovascular disease.