Figure 7. Stronger SIVgag-specific antibodies elicited in mice using the SIVgag-LC3b fusion protein compared to SIVgag antigen alone.

Mice were immunized and serums were collected at week 8 as shown in the Materials and Methods. The SIV-binding antibody was assessed using ELISA. Data were analyzed using the Student’s t-test, and a two-tailed p-value of less than 0.05 was considered statistically significant (*: p<0.05). Each data point represents the antibody titer from an individual mouse (n = 4). The representative data were obtained from two independent experiments.