Figure 4. Morbidity and mortality after ig intoxication with chimeric 122.

Ig intoxication of up to 15 μg 122, 5X the Stx2a LD₅₀ of 2.9 μg [40], did not result in morbidity or mortality. Weight loss was observed after intoxication with 35 and 130 μg 122 (A) and one animal in the 130 μg group succumbed to intoxication on day 4 (B). Error bars represent SEM; 15 μg: n = 10; 35 and 130 μg: n = 5